The unpredictable past of Plasmodium vivax revealed in its genome.
نویسنده
چکیده
منابع مشابه
Clinical Pharmacology of the Antimalarial Chloroquine in Children and Their Mothers
Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and Plasmodium knowlesi are the parasites that infect humans. Plasmodium falciparum and Plasmodium vivax cause most of the malarial infections worldwide. Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and Plasmodium knowlesi are susceptible to chloroquine. Chloroquine was the world's most widely used antim...
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Introduction: The use of Sulfadoxine and pyrimethamine (SP) for treatment of vivax malaria is not common in most of malarious areas because of sensivity of this parasite to chloroquine. But, Plasmodium vivax isolates are exposed to SP because of mixed infection with P.falciparum and this subject has lead to emergence of mutations in P.vdhfr gene. As Plasmodium vivax is the most prevalent specie...
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Mixed malaria infections, Plasmodium falciparum and P. vivax, are suspected to occur at a greater frequency than is detected by conventional light microscopy. In order to determine the year round pattern of transmission and the frequency of mixed infections in malaria endemic area, we carried out a prospective comparison of diagnosis by conventional light microscopy and nested PCR in Chahbahar ...
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Of the four species of malaria parasite known to infect humans, Plasmodium vivax has achieved the widest global distribution, and is responsible for .50% of malaria cases in Central and South America, Asia and the Indian subcontinent [1,2]. Over one billion people are at risk from infection, with 70 million to 80 million cases reported annually. Historically, P. vivax malaria or ‘benign tertian...
متن کاملMitochondrial genome sequences support ancient population expansion in Plasmodium vivax.
Examination of nucleotide diversity in 106 mitochondrial genomes of the most geographically widespread human malaria parasite, Plasmodium vivax, revealed a level of diversity similar to, but slightly higher than, that seen in the virulent human malaria parasite Plasmodium falciparum. The pairwise distribution of nucleotide differences among mitochondrial genome sequences supported the hypothesi...
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 101 44 شماره
صفحات -
تاریخ انتشار 2004